Gabarapl2 | GABA type A receptor associated protein like 2
Physiological systems
20 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Homeostasis/metabolism Immune system Growth/size/body region Hematopoietic system Mortality/aging Cardiovascular system
14 No significant impact
4 Not tested
Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:46Adult tissues
42Embryo tissues
| decreased lymphocyte cell number | 1 supporting dataset | Gabarapl2tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 3.63x10-5 | ||
| increased monocyte cell number | 1 supporting dataset | Gabarapl2tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 1.27x10-6 | ||
| decreased circulating serum albumin level | 1 supporting dataset | Gabarapl2tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 1.91x10-5 | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Gabarapl2tm1b(EUCOMM)Hmgu | homozygote | Early adult | N/A * | ||
| increased neutrophil cell number | 1 supporting dataset | Gabarapl2tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 2.79x10-11 | ||
| decreased hemoglobin content | 1 supporting dataset | Gabarapl2tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 8.89x10-5 | ||
| increased heart weight | 1 supporting dataset | Gabarapl2tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 1.56x10-6 |
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External links
No external links available for Gabarapl2.
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| Gabarapl2tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Gabarapl2tm1b(EUCOMM)Hmgu | Reporter-tagged deletion allele (with selection cassette) | | mouse |