Rad18 | RAD18 E3 ubiquitin protein ligase
Physiological systems
21 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Integument Growth/size/body region Vision/eye Hematopoietic system
17 No significant impact
3 Not tested
Data collections
Gene metrics:8Significant phenotypes
0Associated diseases
Expression examined in:45Adult tissues
0Embryo tissues
| decreased body weight | 5 supporting datasets | Rad18tm1a(EUCOMM)Wtsi | homozygote | Early adult | 3.02x10-11 | ||
| cataract | 1 supporting dataset | Rad18tm1a(EUCOMM)Wtsi | homozygote | Early adult | 2.27x10-5 | ||
| increased mean corpuscular volume | 1 supporting dataset | Rad18tm1a(EUCOMM)Wtsi | homozygote | Early adult | 5.53x10-5 | ||
| abnormal coat/ hair morphology | 1 supporting dataset | Rad18tm1a(EUCOMM)Wtsi | homozygote | Early adult | 4.62x10-5 | ||
| increased hematocrit | 1 supporting dataset | Rad18tm1a(EUCOMM)Wtsi | homozygote | Early adult | 3.95x10-5 | ||
| abnormal lens morphology | 1 supporting dataset | Rad18tm1a(EUCOMM)Wtsi | homozygote | Early adult | 3.72x10-5 | ||
| abnormal hair texture | 1 supporting dataset | Rad18tm1a(EUCOMM)Wtsi | homozygote | Early adult | 4.14x10-5 | ||
| increased body length | 1 supporting dataset | Rad18tm1a(EUCOMM)Wtsi | homozygote | Early adult | 3.94x10-6 |
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External links
No external links available for Rad18.
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| Rad18tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell |
| Rad18tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |