Dach2 | dachshund family transcription factor 2

GeneMGI:1890446Synonyms: 9430028N04Rik

Physiological systems

21 / 24 physiological systems tested

8 Significantly impacted by the knock-out

Reproductive system Immune system Endocrine/exocrine gland Growth/size/body region Vision/eye Hematopoietic system Cardiovascular system Renal/urinary system

13 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:16Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal kidney morphology	1 supporting dataset	Dach2^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal urinary bladder morphology	1 supporting dataset	Dach2^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
enlarged urinary bladder	1 supporting dataset	Dach2^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
anophthalmia	1 supporting dataset	Dach2^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal heart morphology	1 supporting dataset	Dach2^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
enlarged heart	1 supporting dataset	Dach2^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
enlarged spleen	1 supporting dataset	Dach2^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal eye morphology	1 supporting dataset	Dach2^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
enlarged lymph nodes	1 supporting dataset	Dach2^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
increased eosinophil cell number	2 supporting datasets	Dach2^{em1(IMPC)Ccpcz}	homozygote	Early adult	3.41x10^-8

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Dach2.

Associated images

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Histopathology

There is no histopathology data found for Dach2.

IMPC related publications

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External links

No external links available for Dach2.

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*Dach2^{em1(IMPC)Ccpcz}*	Exon Deletion	‌	mouse
*Dach2^{tm231057(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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