Akap10 | A kinase anchor protein 10

GeneMGI:1890218Synonyms: B130049N18Rik, 1500031L16Rik, +1 more

Physiological systems

22 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Hematopoietic system Mortality/aging

20 No significant impact

2 Not tested

Gene metrics:2Significant phenotypes
0Associated diseases
Expression examined in:43Adult tissues
51Embryo tissues

Phenotypes

preweaning lethality, incomplete penetrance3 supporting datasetsAkap10tm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
increased hematocrit1 supporting datasetAkap10tm1.1(KOMP)VlcgheterozygoteEarly adult6.93x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Akap10tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Akap10tm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse
Akap10tm48590(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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