Stx8 | syntaxin 8

GeneMGI:1890156Synonyms: 1110002H11Rik, 4930571E13Rik, +1 more

Physiological systems

20 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Skeleton Mortality/aging

17 No significant impact

4 Not tested

Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:45Adult tissues
0Embryo tissues

Phenotypes

increased circulating alkaline phosphatase level1 supporting datasetStx8tm2a(EUCOMM)WtsihomozygoteEarly adult5.85x10-5 
preweaning lethality, incomplete penetrance1 supporting datasetStx8tm2a(EUCOMM)WtsihomozygoteEarly adultN/A * 
increased lumbar vertebrae number1 supporting datasetStx8tm2a(EUCOMM)WtsihomozygoteEarly adult1.02x10-5 
increased circulating glycerol level1 supporting datasetStx8tm2a(EUCOMM)WtsihomozygoteEarly adult8.37x10-5 
increased lactate dehydrogenase level1 supporting datasetStx8tm2a(EUCOMM)WtsihomozygoteEarly adult9.87x10-9 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Stx8tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Stx8tm1e(EUCOMM)WtsiTargeted, non-conditional allelees cell
Stx8tm2a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Stx8tm2e(EUCOMM)WtsiTargeted, non-conditional allelees cell
Stx8tm3a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell

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