Robo2 | roundabout guidance receptor 2

GeneMGI:1890110Synonyms: 2600013A04Rik, D230004I22Rik, +1 more

Physiological systems

22 / 24 physiological systems tested

8 Significantly impacted by the knock-out

 Homeostasis/metabolism Reproductive system Embryo Growth/size/body region Nervous system Mortality/aging Cardiovascular system Renal/urinary system

14 No significant impact

2 Not tested

Gene metrics:9Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal neural tube morphology1 supporting datasetRobo2em1(IMPC)MbphomozygoteE9.5N/A * 
hemorrhage1 supporting datasetRobo2em1(IMPC)MbphomozygoteE15.5N/A * 
abnormal kidney morphology1 supporting datasetRobo2em1(IMPC)MbpheterozygoteEarly adultN/A * 
preweaning lethality, complete penetrance3 supporting datasetsRobo2em1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal blood vessel morphology1 supporting datasetRobo2em1(IMPC)MbphomozygoteE15.5N/A * 
hydrometra1 supporting datasetRobo2em1(IMPC)MbpheterozygoteEarly adultN/A * 
edema1 supporting datasetRobo2em1(IMPC)MbphomozygoteE15.5N/A * 
enlarged kidney1 supporting datasetRobo2em1(IMPC)MbpheterozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Robo2em1(IMPC)MbpExon Deletionmouse

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