Hibadh | 3-hydroxyisobutyrate dehydrogenase
Physiological systems
19 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Homeostasis/metabolism Integument Vision/eye
16 No significant impact
5 Not tested
Data collections
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:55Adult tissues
0Embryo tissues
| decreased total retina thickness | 2 supporting datasets | Hibadhtm1b(EUCOMM)Wtsi | homozygote | Early adult | 4.23x10-19 | ||
| abnormal skin coloration | 1 supporting dataset | Hibadhtm1b(EUCOMM)Wtsi | homozygote | Early adult | 5.77x10-5 | ||
| abnormal retina inner nuclear layer morphology | 2 supporting datasets | Hibadhtm1b(EUCOMM)Wtsi | homozygote | Early adult | 7.33x10-13 | ||
| decreased fasting circulating glucose level | 1 supporting dataset | Hibadhtm1b(EUCOMM)Wtsi | homozygote | Early adult | 4.63x10-5 | ||
| abnormal eye anterior chamber depth | 1 supporting dataset | Hibadhtm1b(EUCOMM)Wtsi | homozygote | Early adult | 5.58x10-6 | ||
| abnormal retina outer nuclear layer morphology | 1 supporting dataset | Hibadhtm1b(EUCOMM)Wtsi | homozygote | Early adult | 4.5x10-6 |
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External links
No external links available for Hibadh.
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| Hibadhtm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell |
| Hibadhtm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Hibadhtm1b(EUCOMM)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |