Txnip | thioredoxin interacting protein
Physiological systems
18 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Homeostasis/metabolism Adipose tissue Vision/eye Skeleton
14 No significant impact
6 Not tested
Data collections
Gene metrics:8Significant phenotypes
0Associated diseases
Expression examined in:46Adult tissues
0Embryo tissues
| decreased circulating alkaline phosphatase level | 1 supporting dataset | Txniptm1b(EUCOMM)Hmgu | homozygote | Early adult | 3.65x10-8 | ||
| decreased bone mineral content | 2 supporting datasets | Txniptm1b(EUCOMM)Hmgu | homozygote | Early adult | 5.22x10-10 | ||
| decreased bone mineral density | 1 supporting dataset | Txniptm1b(EUCOMM)Hmgu | homozygote | Early adult | 6.53x10-5 | ||
| increased total body fat amount | 2 supporting datasets | Txniptm1b(EUCOMM)Hmgu | homozygote | Early adult | 5.33x10-11 | ||
| increased circulating phosphate level | 1 supporting dataset | Txniptm1b(EUCOMM)Hmgu | homozygote | Early adult | 1.68x10-7 | ||
| increased circulating triglyceride level | 1 supporting dataset | Txniptm1b(EUCOMM)Hmgu | homozygote | Early adult | 1.03x10-20 | ||
| abnormal retina morphology | 1 supporting dataset | Txniptm1b(EUCOMM)Hmgu | homozygote | Early adult | 3.61x10-7 | ||
| increased circulating calcium level | 1 supporting dataset | Txniptm1b(EUCOMM)Hmgu | homozygote | Early adult | 3.52x10-8 |
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External links
No external links available for Txnip.
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| Txniptm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector es cell mouse |
| Txniptm1b(EUCOMM)Hmgu | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Txniptm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | es cell |