Ap1s2 | adaptor-related protein complex 1, sigma 2 subunit
Physiological systems
20 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Homeostasis/metabolism Vision/eye Behavior/neurological
17 No significant impact
4 Not tested
Data collections
Gene metrics:7Significant phenotypes
4Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| abnormal retina morphology | 1 supporting dataset | Ap1s2em1(IMPC)Mbp | homozygote | Early adult | 1.75x10-5 | ||
| increased vertical activity | 1 supporting dataset | Ap1s2em1(IMPC)Mbp | homozygote | Early adult | 1.43x10-11 | ||
| impaired pupillary reflex | 1 supporting dataset | Ap1s2em1(IMPC)Mbp | hemizygote | Early adult | 5.11x10-9 | ||
| abnormal eye morphology | 1 supporting dataset | Ap1s2em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| microphthalmia | 1 supporting dataset | Ap1s2em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| decreased fasting circulating glucose level | 1 supporting dataset | Ap1s2em1(IMPC)Mbp | homozygote | Early adult | 3.29x10-5 |
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External links
No external links available for Ap1s2.
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| Ap1s2em1(IMPC)Mbp | Exon Deletion | | mouse |
| Ap1s2tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell |
| Ap1s2tm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |
| Ap1s2tm2a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Ap1s2tm2e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |