Pdss1 | prenyl (solanesyl) diphosphate synthase, subunit 1
Physiological systems
22 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Reproductive system Endocrine/exocrine gland Growth/size/body region Vision/eye Liver/biliary system Mortality/aging
16 No significant impact
2 Not tested
Data collections
Gene metrics:9Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| preweaning lethality, complete penetrance | 3 supporting datasets | Pdss1em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| prenatal lethality prior to heart atrial septation | 1 supporting dataset | Pdss1em1(IMPC)Mbp | homozygote | E15.5 | N/A * | ||
| abnormal ovary morphology | 1 supporting dataset | Pdss1em1(IMPC)Mbp | heterozygote | Early adult | N/A * | ||
| cataract | 1 supporting dataset | Pdss1em1(IMPC)Mbp | heterozygote | Early adult | 5.06x10-5 | ||
| abnormal retina morphology | 1 supporting dataset | Pdss1em1(IMPC)Mbp | heterozygote | Early adult | 2.32x10-6 | ||
| embryonic lethality prior to organogenesis | 1 supporting dataset | Pdss1em1(IMPC)Mbp | homozygote | E9.5 | N/A * | ||
| abnormal adrenal gland morphology | 1 supporting dataset | Pdss1em1(IMPC)Mbp | heterozygote | Early adult | N/A * | ||
| abnormal liver morphology | 1 supporting dataset | Pdss1em1(IMPC)Mbp | heterozygote | Early adult | N/A * | ||
| enlarged ovary | 1 supporting dataset | Pdss1em1(IMPC)Mbp | heterozygote | Early adult | N/A * |
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External links
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| Pdss1em1(IMPC)Mbp | Exon Deletion | | mouse |
| Pdss1tm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |
| Pdss1tm295534(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |