Dgke | diacylglycerol kinase, epsilon

GeneMGI:1889276Synonyms: DAGK6

Physiological systems

18 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Homeostasis/metabolism Reproductive system Endocrine/exocrine gland Behavior/neurological Skeleton

13 No significant impact

6 Not tested

Gene metrics:5Significant phenotypes
3Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased circulating creatinine level1 supporting datasetDgkeem1(IMPC)TcphomozygoteEarly adult6.27x10-5 
abnormal testis morphology1 supporting datasetDgkeem1(IMPC)TcphomozygoteEarly adultN/A * 
hyperactivity1 supporting datasetDgkeem1(IMPC)TcphomozygoteEarly adult1.06x10-5 
abnormal sternum morphology1 supporting datasetDgkeem1(IMPC)TcphomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Dgkeem1(IMPC)TcpExon Deletionmouse
Dgketm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Dgketm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Dgketm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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