Ntn4 | netrin 4

GeneMGI:1888978Synonyms: beta-netrin

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Immune system Hematopoietic system

15 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:49Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



thrombocytopenia	1 supporting dataset	Ntn4^{tm1b(KOMP)Wtsi}	homozygote	Early adult	1.47x10^-10
decreased hematocrit	1 supporting dataset	Ntn4^{tm1b(KOMP)Wtsi}	homozygote	Early adult	3.64x10^-5
abnormal spleen morphology	1 supporting dataset	Ntn4^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Ntn4.

Associated images

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Histopathology

There is no histopathology data found for Ntn4.

IMPC related publications

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External links

No external links available for Ntn4.

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*Ntn4^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Ntn4^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse

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