Fzd2 | frizzled class receptor 2

GeneMGI:1888513Synonyms: Mfz10a, Fz10, +1 more

Physiological systems

22 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Behavior/neurological Mortality/aging

20 No significant impact

2 Not tested

Gene metrics:4Significant phenotypes
3Associated diseases
Expression examined in:73Adult tissues
30Embryo tissues

Phenotypes

preweaning lethality, complete penetrance3 supporting datasetsFzd2tm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
hyperactivity1 supporting datasetFzd2tm1.1(KOMP)VlcgheterozygoteEarly adult9.66x10-5 
embryonic lethality prior to organogenesis1 supporting datasetFzd2tm1.1(KOMP)VlcghomozygoteE9.5N/A * 
embryonic lethality prior to tooth bud stage1 supporting datasetFzd2tm1.1(KOMP)VlcghomozygoteE12.5N/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Fzd2tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Fzd2tm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse
Fzd2tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Fzd2tm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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