Tbx20 | T-box 20

GeneMGI:1888496Synonyms: Tbx12, 9430010M06Rik

Physiological systems

22 / 24 physiological systems tested

9 Significantly impacted by the knock-out

Immune system Embryo Nervous system Vision/eye Hearing/vestibular/ear Hematopoietic system Craniofacial Cardiovascular system Mortality/aging

13 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:18Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



abnormal blood vessel morphology	1 supporting dataset	Tbx20^em1(IMPC)Mbp	homozygote	E9.5	N/A ^*
abnormal optic vesicle formation	1 supporting dataset	Tbx20^em1(IMPC)Mbp	homozygote	E9.5	N/A ^*
hemorrhage	1 supporting dataset	Tbx20^em1(IMPC)Mbp	homozygote	E9.5	N/A ^*
abnormal forebrain development	1 supporting dataset	Tbx20^em1(IMPC)Mbp	homozygote	E9.5	N/A ^*
abnormal otic vesicle morphology	1 supporting dataset	Tbx20^em1(IMPC)Mbp	homozygote	E9.5	N/A ^*
abnormal vitelline vasculature morphology	1 supporting dataset	Tbx20^em1(IMPC)Mbp	homozygote	E9.5	N/A ^*
abnormal pharyngeal arch morphology	1 supporting dataset	Tbx20^em1(IMPC)Mbp	homozygote	E9.5	N/A ^*
abnormal placenta morphology	1 supporting dataset	Tbx20^em1(IMPC)Mbp	heterozygote	E15.5	N/A ^*
abnormal heart morphology	1 supporting dataset	Tbx20^em1(IMPC)Mbp	homozygote	E9.5	N/A ^*
preweaning lethality, complete penetrance	3 supporting datasets	Tbx20^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Tbx20.

Associated images

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Histopathology

There is no histopathology data found for Tbx20.

IMPC related publications

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External links

No external links available for Tbx20.

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*Tbx20^em1(IMPC)Mbp*	Exon Deletion	‌	mouse
*Tbx20^{tm1(NCOM)Mfgc}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector ES Cell
*Tbx20^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Tbx20^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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