H2az1 | H2A.Z variant histone 1

GeneMGI:1888388Synonyms: H2A.Z1, H2A.Z, +1 more

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Behavior/neurological Mortality/aging

15 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



embryonic lethality prior to organogenesis	1 supporting dataset	H2az1^em1(IMPC)J	homozygote	E9.5	N/A ^*
decreased circulating total protein level	1 supporting dataset	H2az1^em1(IMPC)J	heterozygote	Early adult	9.52x10^-5
increased startle reflex	1 supporting dataset	H2az1^em1(IMPC)J	heterozygote	Early adult	1.02x10^-6
preweaning lethality, complete penetrance	1 supporting dataset	H2az1^em1(IMPC)J	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for H2az1.

Associated images

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Histopathology

There is no histopathology data found for H2az1.

IMPC related publications

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External links

No external links available for H2az1.

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*H2az1^em1(IMPC)J*	Whole-gene deletion	‌	mouse
*H2az1^{tm1(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector ES Cell
*H2az1^{tm270828(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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