Wwp1 | WW domain containing E3 ubiquitin protein ligase 1

GeneMGI:1861728Synonyms: SDRP1, Tiul1, +2 more

Physiological systems

19 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Limbs/digits/tail Behavior/neurological Skeleton

15 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:

Life Stage:



decreased fasting circulating glucose level	1 supporting dataset	Wwp1^em1(IMPC)H	homozygote	Late adult	6.84x10^-5
decreased locomotor activity	1 supporting dataset	Wwp1^em1(IMPC)H	homozygote	Early adult	1.72x10^-5
short tibia	1 supporting dataset	Wwp1^em1(IMPC)H	homozygote	Early adult	3.59x10^-8
increased circulating phosphate level	1 supporting dataset	Wwp1^em1(IMPC)H	homozygote	Early adult	4.9x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Wwp1.

Associated images

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Histopathology

There is no histopathology data found for Wwp1.

IMPC related publications

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External links

No external links available for Wwp1.

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*Wwp1^em1(IMPC)H*	Exon Deletion	‌	mouse
*Wwp1^{em1(IMPC)Marc}*	Deletion	‌	mouse

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