Aldh1a3 | aldehyde dehydrogenase family 1, subfamily A3
Physiological systems
20 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Homeostasis/metabolism Vision/eye Behavior/neurological Mortality/aging
16 No significant impact
4 Not tested
Gene metrics:4Significant phenotypes
3Associated diseases
Expression examined in:48Adult tissues
50Embryo tissues
| microphthalmia | 1 supporting dataset | Aldh1a3tm1b(KOMP)Wtsi | homozygote | E15.5 | N/A * | ||
| increased circulating alkaline phosphatase level | 1 supporting dataset | Aldh1a3tm1b(KOMP)Wtsi | heterozygote | Early adult | 6.5x10-5 | ||
| hyperactivity | 8 supporting datasets | Aldh1a3tm1b(KOMP)Wtsi | heterozygote | Early adult | 1.01x10-7 | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Aldh1a3tm1b(KOMP)Wtsi | homozygote | Early adult | N/A * |
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External links
No external links available for Aldh1a3.
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| Aldh1a3tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Aldh1a3tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Aldh1a3tm1b(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Aldh1a3tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |
| Aldh1a3tm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |
| Aldh1a3tm357331(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |