Dynll1 | dynein light chain LC8-type 1

GeneMGI:1861457Synonyms: DLC8, Dnclc1, +2 more

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Homeostasis/metabolism Mortality/aging

15 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



increased circulating bilirubin level	1 supporting dataset	Dynll1^{tm1(KOMP)Wtsi}	heterozygote	Early adult	1.09x10^-5
increased circulating alkaline phosphatase level	1 supporting dataset	Dynll1^{tm1(KOMP)Wtsi}	heterozygote	Early adult	3.9x10^-6
decreased circulating glucose level	1 supporting dataset	Dynll1^{tm1(KOMP)Wtsi}	heterozygote	Early adult	7.53x10^-5
preweaning lethality, complete penetrance	1 supporting dataset	Dynll1^{tm1(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
decreased circulating fructosamine level	1 supporting dataset	Dynll1^{tm1(KOMP)Wtsi}	heterozygote	Early adult	1.66x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Dynll1.

Associated images

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Histopathology

There is no histopathology data found for Dynll1.

IMPC related publications

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External links

No external links available for Dynll1.

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*Dynll1^tm1(KOMP)Mbp*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector es cell
*Dynll1^{tm1(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector es cell mouse

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