Actl6a | actin-like 6A

GeneMGI:1861453Synonyms: Actl6, Baf53a, +2 more

Physiological systems

18 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Hematopoietic system Behavior/neurological Mortality/aging

14 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:5Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased mean corpuscular hemoglobin1 supporting datasetActl6aem1(IMPC)JheterozygoteEarly adult4.57x10-5 
decreased exploration in new environment1 supporting datasetActl6aem1(IMPC)JheterozygoteEarly adult4.75x10-6 
decreased circulating phosphate level1 supporting datasetActl6aem1(IMPC)JheterozygoteEarly adult1.54x10-5 
decreased circulating bilirubin level1 supporting datasetActl6aem1(IMPC)JheterozygoteEarly adult3.06x10-6 
preweaning lethality, complete penetrance1 supporting datasetActl6aem1(IMPC)JhomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
Download data as:  










* This parameter was manually assessed for significance.
Download data as:  

lacZ Expression

Associated images

Loading...

Histopathology

IMPC related publications

Loading...

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

Actl6aem1(IMPC)JExon Deletionmouse
Actl6atm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Actl6atm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter