Ptbp2 | polypyrimidine tract binding protein 2

GeneMGI:1860489Synonyms: brPTB

Physiological systems

20 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Integument Growth/size/body region Vision/eye Skeleton Mortality/aging Craniofacial

14 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



abnormal tooth morphology	2 supporting datasets	Ptbp2^{em1(IMPC)Hmgu}	heterozygote	Early adult	2.21x10^-5
decreased total retina thickness	1 supporting dataset	Ptbp2^{em1(IMPC)Hmgu}	heterozygote	Early adult	8.36x10^-7
abnormal vibrissa morphology	1 supporting dataset	Ptbp2^{em1(IMPC)Hmgu}	heterozygote	Early adult	1.88x10^-5
preweaning lethality, complete penetrance	1 supporting dataset	Ptbp2^{em1(IMPC)Hmgu}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Ptbp2.

Associated images

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Histopathology

There is no histopathology data found for Ptbp2.

IMPC related publications

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External links

No external links available for Ptbp2.

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*Ptbp2^{em1(IMPC)Hmgu}*	Exon Deletion	‌	mouse
*Ptbp2^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Ptbp2^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell
*Ptbp2^{tm2a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell

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