Psmg1 | proteasome (prosome, macropain) assembly chaperone 1

GeneMGI:1860263Synonyms: Dscr2

Physiological systems

20 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Embryo Growth/size/body region Nervous system Vision/eye Behavior/neurological Mortality/aging Craniofacial

13 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:11Significant phenotypes

0Associated diseases

Expression examined in:50Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



preweaning lethality, complete penetrance	3 supporting datasets	Psmg1^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
abnormal visceral yolk sac morphology	1 supporting dataset	Psmg1^{tm1b(KOMP)Wtsi}	heterozygote	E9.5	N/A ^*
abnormal neural tube closure	1 supporting dataset	Psmg1^{tm1b(KOMP)Wtsi}	heterozygote	E9.5	N/A ^*
abnormal pharyngeal arch morphology	1 supporting dataset	Psmg1^{tm1b(KOMP)Wtsi}	heterozygote	E9.5	N/A ^*
cornea opacity	1 supporting dataset	Psmg1^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	9.85x10^-6
abnormal embryo turning	1 supporting dataset	Psmg1^{tm1b(KOMP)Wtsi}	heterozygote	E9.5	N/A ^*
hyperactivity	1 supporting dataset	Psmg1^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	9.73x10^-5
abnormal embryo size	1 supporting dataset	Psmg1^{tm1b(KOMP)Wtsi}	heterozygote	E9.5	N/A ^*
abnormal neural tube morphology	1 supporting dataset	Psmg1^{tm1b(KOMP)Wtsi}	heterozygote	E9.5	N/A ^*
embryonic growth retardation	1 supporting dataset	Psmg1^{tm1b(KOMP)Wtsi}	heterozygote	E9.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Psmg1.

Associated images

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Histopathology

There is no histopathology data found for Psmg1.

IMPC related publications

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External links

No external links available for Psmg1.

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*Psmg1^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Psmg1^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Psmg1^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Psmg1^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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