Crlf3 | cytokine receptor-like factor 3

GeneMGI:1860086Synonyms: Creme9, cytor4

Physiological systems

21 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Growth/size/body region Hematopoietic system Behavior/neurological

17 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:7Significant phenotypes

0Associated diseases

Expression examined in:45Adult tissues

0Embryo tissues

Phenotypes

Allele:

Phy. System:



thrombocytopenia	1 supporting dataset	Crlf3^{em1(IMPC)Wtsi}	homozygote	Early adult	9.54x10^-13
thrombocytopenia	2 supporting datasets	Crlf3^{tm1a(KOMP)Wtsi}	homozygote	Early adult	4.54x10^-10
thrombocytopenia	1 supporting dataset	Crlf3^{tm1b(KOMP)Wtsi}	homozygote	Early adult	2.53x10^-7
abnormal behavior	1 supporting dataset	Crlf3^{tm1a(KOMP)Wtsi}	homozygote	Early adult	2.35x10^-5
decreased body weight	1 supporting dataset	Crlf3^{tm1a(KOMP)Wtsi}	homozygote	Early adult	4.37x10^-17
decreased mean corpuscular volume	1 supporting dataset	Crlf3^{tm1b(KOMP)Wtsi}	homozygote	Early adult	1.93x10^-7
increased red blood cell distribution width	1 supporting dataset	Crlf3^{em1(IMPC)Wtsi}	homozygote	Early adult	9.09x10^-10
tremors	1 supporting dataset	Crlf3^{tm1a(KOMP)Wtsi}	homozygote	Early adult	8.93x10^-5
increased circulating iron level	1 supporting dataset	Crlf3^{tm1a(KOMP)Wtsi}	homozygote	Early adult	9.48x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Crlf3.

Associated images

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Histopathology

There is no histopathology data found for Crlf3.

IMPC related publications

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External links

No external links available for Crlf3.

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*Crlf3^{em1(IMPC)Wtsi}*	Deletion	‌	mouse
*Crlf3^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Crlf3^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Crlf3^{tm1c(KOMP)Wtsi}*	Wild type floxed exon (post-Flp)	‌	mouse
*Crlf3^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	es cell
*Crlf3^{tm356713(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*Crlf3^{tm38187(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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