Syt8 | synaptotagmin VIII

Physiological systems

17 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Nervous system Vision/eye Behavior/neurological

14 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal optic disk morphology1 supporting datasetSyt8em1(IMPC)JhomozygoteEarly adult3.87x10-5 
limb grasping1 supporting datasetSyt8em1(IMPC)JhomozygoteEarly adult2.06x10-5 
decreased grip strength1 supporting datasetSyt8em1(IMPC)JhomozygoteEarly adult1.64x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Syt8em1(IMPC)JExon Deletionmouse
Syt8tm1(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)targeting vector
es cell
Syt8tm450603(L1L2_GT0_LF2A_LacZ_BetactP_neo)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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