Atp11c | ATPase, class VI, type 11C

GeneMGI:1859661Synonyms: A330005H02Rik, Ig

Physiological systems

16 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Hematopoietic system

13 No significant impact

8 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:11Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased erythrocyte cell number1 supporting datasetAtp11cem1(IMPC)JhemizygoteEarly adult1.17x10-10 
increased circulating bilirubin level1 supporting datasetAtp11cem1(IMPC)JhomozygoteEarly adult0 
increased circulating alkaline phosphatase level1 supporting datasetAtp11cem1(IMPC)JhomozygoteEarly adult7.04x10-12 
increased circulating bilirubin level1 supporting datasetAtp11cem1(IMPC)JhemizygoteEarly adult0 
decreased erythrocyte cell number1 supporting datasetAtp11cem1(IMPC)JhomozygoteEarly adult3.01x10-9 
decreased hematocrit1 supporting datasetAtp11cem1(IMPC)JhomozygoteEarly adult3.08x10-8 
decreased hematocrit1 supporting datasetAtp11cem1(IMPC)JhemizygoteEarly adult4.28x10-6 
decreased hemoglobin content1 supporting datasetAtp11cem1(IMPC)JhemizygoteEarly adult8.15x10-6 
increased mean corpuscular hemoglobin1 supporting datasetAtp11cem1(IMPC)JhemizygoteEarly adult3.76x10-8 
abnormal cholesterol homeostasis1 supporting datasetAtp11cem1(IMPC)JhemizygoteEarly adult2.06x10-10 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Atp11cem1(IMPC)JExon Deletionmouse
Atp11ctm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Atp11ctm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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