Mtx2 | metaxin 2

GeneMGI:1859652Synonyms: 1500012G02Rik

Physiological systems

18 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Hematopoietic system Skeleton Mortality/aging

13 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



preweaning lethality, complete penetrance	1 supporting dataset	Mtx2^em1(IMPC)J	homozygote	Early adult	N/A ^*
increased bone mineral density	1 supporting dataset	Mtx2^em1(IMPC)J	heterozygote	Early adult	1.37x10^-5
embryonic lethality prior to organogenesis	1 supporting dataset	Mtx2^em1(IMPC)J	homozygote	E9.5	N/A ^*
decreased leukocyte cell number	1 supporting dataset	Mtx2^em1(IMPC)J	heterozygote	Early adult	8.51x10^-8
decreased circulating glucose level	1 supporting dataset	Mtx2^em1(IMPC)J	heterozygote	Early adult	1.05x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Mtx2.

Associated images

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Histopathology

There is no histopathology data found for Mtx2.

IMPC related publications

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External links

No external links available for Mtx2.

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*Mtx2^em1(IMPC)J*	Exon Deletion	‌	mouse
*Mtx2^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse

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