Dnmt3l | DNA methyltransferase 3-like
Physiological systems
21 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Reproductive system Endocrine/exocrine gland Vision/eye Hematopoietic system Skeleton
16 No significant impact
3 Not tested
Data collections
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| small testis | 1 supporting dataset | Dnmt3ltm1b(EUCOMM)Hmgu | homozygote | Early adult | N/A * | ||
| persistence of hyaloid vascular system | 1 supporting dataset | Dnmt3ltm1b(EUCOMM)Hmgu | homozygote | Early adult | 3.76x10-5 | ||
| increased bone mineral density | 1 supporting dataset | Dnmt3ltm1b(EUCOMM)Hmgu | homozygote | Early adult | 2.08x10-5 | ||
| male infertility | 1 supporting dataset | Dnmt3lem1(IMPC)Bay | homozygote | Early adult | N/A * | ||
| female infertility | 1 supporting dataset | Dnmt3lem1(IMPC)Bay | homozygote | Early adult | N/A * | ||
| increased mean corpuscular hemoglobin | 1 supporting dataset | Dnmt3ltm1b(EUCOMM)Hmgu | homozygote | Early adult | 8.34x10-5 |
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External links
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| Dnmt3lem1(IMPC)Bay | Exon Deletion | | mouse |
| Dnmt3ltm1(NCOM)Mfgc | Reporter-tagged deletion allele (with selection cassette) | | targeting vector es cell |
| Dnmt3ltm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector es cell mouse |
| Dnmt3ltm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | es cell |
| Dnmt3ltm1b(EUCOMM)Hmgu | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Dnmt3ltm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | es cell |