Irf3 | interferon regulatory factor 3

GeneMGI:1859179Synonyms: C920001K05Rik, IRF-3

Physiological systems

20 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Behavior/neurological Renal/urinary system

16 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:6Significant phenotypes

1Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



hyperactivity	2 supporting datasets	Irf3^em1(IMPC)Mbp	homozygote	Early adult	9.18x10^-5
increased circulating phosphate level	1 supporting dataset	Irf3^em1(IMPC)Mbp	homozygote	Early adult	2.11x10^-5
increased circulating alkaline phosphatase level	1 supporting dataset	Irf3^em1(IMPC)Mbp	homozygote	Early adult	8.1x10^-5
enlarged lymph nodes	1 supporting dataset	Irf3^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal kidney morphology	1 supporting dataset	Irf3^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
small kidney	1 supporting dataset	Irf3^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Irf3.

Associated images

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Histopathology

There is no histopathology data found for Irf3.

IMPC related publications

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External links

No external links available for Irf3.

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*Irf3^em1(IMPC)Mbp*	Exon Deletion	‌	mouse

My Genes