Pdcd7 | programmed cell death 7

GeneMGI:1859170Synonyms: ES18

Physiological systems

22 / 24 physiological systems tested

9 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Endocrine/exocrine gland Embryo Vision/eye Liver/biliary system Hematopoietic system Mortality/aging Cardiovascular system

13 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:15Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



small liver	1 supporting dataset	Pdcd7^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*
increased heart rate	1 supporting dataset	Pdcd7^em1(IMPC)Mbp	heterozygote	Early adult	1.06x10^-5
abnormal placenta morphology	1 supporting dataset	Pdcd7^em1(IMPC)Mbp	heterozygote	E15.5	N/A ^*
preweaning lethality, complete penetrance	3 supporting datasets	Pdcd7^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
enlarged testis	1 supporting dataset	Pdcd7^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*
small seminal vesicle	1 supporting dataset	Pdcd7^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*
abnormal liver morphology	1 supporting dataset	Pdcd7^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*
decreased circulating serum albumin level	1 supporting dataset	Pdcd7^em1(IMPC)Mbp	heterozygote	Early adult	9.37x10^-6
microphthalmia	1 supporting dataset	Pdcd7^em1(IMPC)Mbp	heterozygote	E15.5	N/A ^*
embryonic lethality prior to organogenesis	1 supporting dataset	Pdcd7^em1(IMPC)Mbp	homozygote	E9.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Pdcd7.

Associated images

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Histopathology

There is no histopathology data found for Pdcd7.

IMPC related publications

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External links

No external links available for Pdcd7.

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*Pdcd7^em1(IMPC)Mbp*	Exon Deletion	‌	mouse
*Pdcd7^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Pdcd7^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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