Mcrs1 | microspherule protein 1

GeneMGI:1858420Synonyms: P78, MSP58, +2 more

Physiological systems

20 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Homeostasis/metabolism Mortality/aging

18 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:48Adult tissues

25Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



preweaning lethality, complete penetrance	1 supporting dataset	Mcrs1^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
increased circulating chloride level	1 supporting dataset	Mcrs1^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	1.66x10^-5
embryonic lethality prior to organogenesis	1 supporting dataset	Mcrs1^{tm1.1(KOMP)Vlcg}	homozygote	E9.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Mcrs1.

Associated images

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Histopathology

There is no histopathology data found for Mcrs1.

IMPC related publications

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External links

No external links available for Mcrs1.

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*Mcrs1^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Mcrs1^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Mcrs1^{tm299516(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*Mcrs1^{tm299516(L1L2_gt2_Del_LacZ)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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