Gal3st1 | galactose-3-O-sulfotransferase 1

GeneMGI:1858277Synonyms: 3'-phosphoadenylylsulfate-galactosylceramide 3'-sulfotransferase, Cst, +3 more

Physiological systems

14 / 24 physiological systems tested

8 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Endocrine/exocrine gland Limbs/digits/tail Nervous system Liver/biliary system Behavior/neurological Skeleton

6 No significant impact

10 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:17Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



small testis	1 supporting dataset	Gal3st1^{em1(IMPC)Rbrc}	homozygote	Early adult	N/A ^*
short tibia	1 supporting dataset	Gal3st1^{em1(IMPC)Rbrc}	homozygote	Early adult	4.65x10^-5
abnormal vertebral arch morphology	2 supporting datasets	Gal3st1^{em1(IMPC)Rbrc}	homozygote	Early adult	2.39x10^-6
tremors	1 supporting dataset	Gal3st1^{em1(IMPC)Rbrc}	homozygote	Early adult	1.71x10^-15
abnormal brain morphology	2 supporting datasets	Gal3st1^{em1(IMPC)Rbrc}	homozygote	Early adult	N/A ^*
small liver	2 supporting datasets	Gal3st1^{em1(IMPC)Rbrc}	homozygote	Early adult	N/A ^*
decreased locomotor activity	8 supporting datasets	Gal3st1^{em1(IMPC)Rbrc}	homozygote	Early adult	4.74x10^-9
abnormal testis morphology	1 supporting dataset	Gal3st1^{em1(IMPC)Rbrc}	homozygote	Early adult	N/A ^*
increased thigmotaxis	2 supporting datasets	Gal3st1^{em1(IMPC)Rbrc}	homozygote	Early adult	9.37x10^-12
abnormal liver morphology	2 supporting datasets	Gal3st1^{em1(IMPC)Rbrc}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Gal3st1.

Associated images

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Histopathology

There is no histopathology data found for Gal3st1.

IMPC related publications

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External links

No external links available for Gal3st1.

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*Gal3st1^{em1(IMPC)Rbrc}*	Intra-exon deletion	‌	mouse
*Gal3st1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Gal3st1^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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