Tomm40 | translocase of outer mitochondrial membrane 40

GeneMGI:1858259Synonyms: Tom40

Physiological systems

17 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Vision/eye Hematopoietic system Behavior/neurological Mortality/aging

13 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:8Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

preweaning lethality, complete penetrance1 supporting datasetTomm40em1(IMPC)JhomozygoteEarly adultN/A * 
abnormal startle reflex1 supporting datasetTomm40em1(IMPC)JheterozygoteEarly adult1.55x10-11 
decreased mean corpuscular hemoglobin1 supporting datasetTomm40em1(IMPC)JheterozygoteEarly adult2.93x10-13 
persistence of hyaloid vascular system1 supporting datasetTomm40em1(IMPC)JheterozygoteEarly adult6.73x10-6 
hyperactivity2 supporting datasetsTomm40em1(IMPC)JheterozygoteEarly adult1.06x10-6 
decreased mean corpuscular hemoglobin concentration1 supporting datasetTomm40em1(IMPC)JheterozygoteEarly adult2.62x10-5 
cataract1 supporting datasetTomm40em1(IMPC)JheterozygoteEarly adult9.65x10-5 
embryonic lethality prior to organogenesis1 supporting datasetTomm40em1(IMPC)JhomozygoteE9.5N/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Tomm40em1(IMPC)JExon Deletionmouse

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