Tomm40 | translocase of outer mitochondrial membrane 40
Physiological systems
17 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Vision/eye Hematopoietic system Behavior/neurological Mortality/aging
13 No significant impact
7 Not tested
Data collections
Gene metrics:8Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
preweaning lethality, complete penetrance | 1 supporting dataset | Tomm40em1(IMPC)J | homozygote | Early adult | N/A * | ||
abnormal startle reflex | 1 supporting dataset | Tomm40em1(IMPC)J | heterozygote | Early adult | 1.55x10-11 | ||
decreased mean corpuscular hemoglobin | 1 supporting dataset | Tomm40em1(IMPC)J | heterozygote | Early adult | 2.93x10-13 | ||
persistence of hyaloid vascular system | 1 supporting dataset | Tomm40em1(IMPC)J | heterozygote | Early adult | 6.73x10-6 | ||
hyperactivity | 2 supporting datasets | Tomm40em1(IMPC)J | heterozygote | Early adult | 1.06x10-6 | ||
decreased mean corpuscular hemoglobin concentration | 1 supporting dataset | Tomm40em1(IMPC)J | heterozygote | Early adult | 2.62x10-5 | ||
cataract | 1 supporting dataset | Tomm40em1(IMPC)J | heterozygote | Early adult | 9.65x10-5 | ||
embryonic lethality prior to organogenesis | 1 supporting dataset | Tomm40em1(IMPC)J | homozygote | E9.5 | N/A * |
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External links
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Tomm40em1(IMPC)J | Exon Deletion | | mouse |