Mpp2 | membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)

GeneMGI:1858257Synonyms: Dlgh2, Dlg2, +2 more

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Homeostasis/metabolism Vision/eye

16 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

0Associated diseases

Expression examined in:50Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal retina outer nuclear layer morphology	1 supporting dataset	Mpp2^{tm1b(KOMP)Wtsi}	homozygote	Early adult	2.08x10^-6
decreased total retina thickness	2 supporting datasets	Mpp2^{tm1b(KOMP)Wtsi}	homozygote	Early adult	7.16x10^-9
impaired glucose tolerance	1 supporting dataset	Mpp2^{tm1b(KOMP)Wtsi}	homozygote	Early adult	2.58x10^-5
abnormal retina inner nuclear layer morphology	2 supporting datasets	Mpp2^{tm1b(KOMP)Wtsi}	homozygote	Early adult	1.48x10^-8

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Mpp2.

Associated images

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Histopathology

There is no histopathology data found for Mpp2.

IMPC related publications

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External links

No external links available for Mpp2.

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*Mpp2^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Mpp2^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse

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