Nudt5 | nudix hydrolase 5

GeneMGI:1858232Synonyms: nudix (nucleoside diphosphate linked moiety X)-type motif 5

Physiological systems

16 / 24 physiological systems tested

1 Significantly impacted by the knock-out

 Vision/eye

15 No significant impact

8 Not tested

Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:50Adult tissues
0Embryo tissues

Phenotypes

decreased total retina thickness2 supporting datasetsNudt5tm1b(EUCOMM)HmguhomozygoteEarly adult5x10-12 
abnormal eye posterior chamber depth1 supporting datasetNudt5tm1b(EUCOMM)HmguhomozygoteEarly adult1.42x10-8 
abnormal retina inner nuclear layer morphology2 supporting datasetsNudt5tm1b(EUCOMM)HmguhomozygoteEarly adult3.44x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Nudt5tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Nudt5tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
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Nudt5tm1b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
Nudt5tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell
Nudt5tm2a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
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Nudt5tm2e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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