Cdkl2 | cyclin dependent kinase like 2
Physiological systems
17 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Homeostasis/metabolism Immune system Hematopoietic system Skeleton
13 No significant impact
7 Not tested
Data collections
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:51Adult tissues
0Embryo tissues
decreased circulating phosphate level | 1 supporting dataset | Cdkl2tm1b(EUCOMM)Hmgu | homozygote | Early adult | 3.12x10-6 | ||
abnormal spleen morphology | 2 supporting datasets | Cdkl2tm1b(EUCOMM)Hmgu | homozygote | Early adult | N/A * | ||
decreased circulating aspartate transaminase level | 1 supporting dataset | Cdkl2tm1b(EUCOMM)Hmgu | homozygote | Early adult | 2.06x10-6 | ||
decreased bone mineral content | 1 supporting dataset | Cdkl2tm1b(EUCOMM)Hmgu | homozygote | Early adult | 4.87x10-5 | ||
decreased circulating potassium level | 1 supporting dataset | Cdkl2tm1b(EUCOMM)Hmgu | homozygote | Early adult | 3.5x10-5 |
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External links
No external links available for Cdkl2.
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Cdkl2tm1(NCOM)Mfgc | Reporter-tagged deletion allele (with selection cassette) | | targeting vector ES Cell |
Cdkl2tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
Cdkl2tm1b(EUCOMM)Hmgu | Reporter-tagged deletion allele (with selection cassette) | | mouse |
Cdkl2tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |