Atp5f1e | ATP synthase F1 subunit epsilon

GeneMGI:1855697Synonyms: 2410043G19Rik, Atp5e

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Hematopoietic system Mortality/aging

16 No significant impact

6 Not tested

Gene metrics:4Significant phenotypes
2Associated diseases
Expression examined in:45Adult tissues
0Embryo tissues

Phenotypes

embryonic lethality prior to organogenesis1 supporting datasetAtp5f1etm1b(EUCOMM)WtsihomozygoteE9.5N/A * 
preweaning lethality, complete penetrance1 supporting datasetAtp5f1etm1b(EUCOMM)WtsihomozygoteEarly adultN/A * 
increased red blood cell distribution width1 supporting datasetAtp5f1etm1b(EUCOMM)WtsiheterozygoteEarly adult1.71x10-6 
prenatal lethality prior to heart atrial septation1 supporting datasetAtp5f1etm1b(EUCOMM)WtsihomozygoteE15.5N/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Atp5f1etm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Atp5f1etm1b(EUCOMM)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Atp5f1etm1e(EUCOMM)WtsiTargeted, non-conditional allelees cell

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