Slc7a8 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 8

GeneMGI:1355323Synonyms: LAT2

Physiological systems

16 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Limbs/digits/tail Skeleton

13 No significant impact

8 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

0Associated diseases

Expression examined in:46Adult tissues

42Embryo tissues

Phenotypes

Phy. System:



short tibia	1 supporting dataset	Slc7a8^{tm2b(EUCOMM)Hmgu}	heterozygote	Early adult	3.02x10^-5
decreased circulating fructosamine level	1 supporting dataset	Slc7a8^{tm2b(EUCOMM)Hmgu}	heterozygote	Early adult	8.36x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Slc7a8.

Associated images

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Histopathology

There is no histopathology data found for Slc7a8.

IMPC related publications

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External links

No external links available for Slc7a8.

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*Slc7a8^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Slc7a8^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell
*Slc7a8^{tm2a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Slc7a8^{tm2b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Slc7a8^{tm2e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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