Copb2 | COPI coat complex subunit beta 2
GeneMGI:1354962
Physiological systems
21 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Adipose tissue Growth/size/body region Vision/eye Behavior/neurological Cardiovascular system Mortality/aging
15 No significant impact
3 Not tested
Data collections
Gene metrics:7Significant phenotypes
3Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| preweaning lethality, complete penetrance | 3 supporting datasets | Copb2em1(IMPC)Bay | homozygote | Early adult | N/A * | ||
| decreased grip strength | 1 supporting dataset | Copb2em1(IMPC)Bay | heterozygote | Early adult | 5.17x10-5 | ||
| increased lean body mass | 2 supporting datasets | Copb2em1(IMPC)Bay | heterozygote | Early adult | 7.41x10-9 | ||
| decreased total body fat amount | 2 supporting datasets | Copb2em1(IMPC)Bay | heterozygote | Early adult | 6.38x10-8 | ||
| prenatal lethality | 1 supporting dataset | Copb2em1(IMPC)Bay | homozygote | E18.5 | N/A * | ||
| decreased locomotor activity | 1 supporting dataset | Copb2em1(IMPC)Bay | heterozygote | Early adult | 8.45x10-5 | ||
| abnormal retina vasculature morphology | 1 supporting dataset | Copb2em1(IMPC)Bay | heterozygote | Early adult | 9.02x10-6 |
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External links
No external links available for Copb2.
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| Copb2em1(IMPC)Bay | Exon Deletion | | mouse |
| Copb2tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Copb2tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Copb2tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |