Synj1 | synaptojanin 1
Physiological systems
17 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Immune system Vision/eye Hematopoietic system Behavior/neurological Mortality/aging
12 No significant impact
7 Not tested
Gene metrics:7Significant phenotypes
5Associated diseases
Expression examined in:46Adult tissues
42Embryo tissues
| decreased red blood cell distribution width | 1 supporting dataset | Synj1tm1b(EUCOMM)Wtsi | heterozygote | Early adult | 2.06x10-7 | ||
| decreased neutrophil cell number | 1 supporting dataset | Synj1tm1b(EUCOMM)Wtsi | heterozygote | Early adult | 1.19x10-15 | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Synj1tm1b(EUCOMM)Wtsi | homozygote | Early adult | N/A * | ||
| persistence of hyaloid vascular system | 1 supporting dataset | Synj1tm1b(EUCOMM)Wtsi | heterozygote | Early adult | 5.22x10-7 | ||
| tremors | 1 supporting dataset | Synj1tm1b(EUCOMM)Wtsi | heterozygote | Early adult | 6.6x10-7 | ||
| increased lymphocyte cell number | 1 supporting dataset | Synj1tm1b(EUCOMM)Wtsi | heterozygote | Early adult | 1.88x10-13 | ||
| decreased monocyte cell number | 1 supporting dataset | Synj1tm1b(EUCOMM)Wtsi | heterozygote | Early adult | 6.02x10-7 |
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External links
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| Synj1tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector es cell mouse |
| Synj1tm1b(EUCOMM)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Synj1tm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | es cell |