Dkk3 | dickkopf WNT signaling pathway inhibitor 3

GeneMGI:1354952

Physiological systems

13 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Digestive/alimentary Hematopoietic system

11 No significant impact

11 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased mean corpuscular hemoglobin concentration	1 supporting dataset	Dkk3^tm1Cni	homozygote	Early adult	7.02x10^-7
increased cellular hemoglobin content	1 supporting dataset	Dkk3^tm1Cni	homozygote	Early adult	9.8x10^-6
increased defecation amount	1 supporting dataset	Dkk3^tm1Cni	homozygote	Early adult	9.15x10^-5
increased mean corpuscular volume	1 supporting dataset	Dkk3^tm1Cni	homozygote	Early adult	2.06x10^-11

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Dkk3.

Associated images

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Histopathology

There is no histopathology data found for Dkk3.

IMPC related publications

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External links

No external links available for Dkk3.

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*Dkk3^{tm1(EGFP/cre/ERT2)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Dkk3^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Dkk3^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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