Mapk6 | mitogen-activated protein kinase 6
Physiological systems
22 / 24 physiological systems tested
7 Significantly impacted by the knock-out
Homeostasis/metabolism Reproductive system Embryo Nervous system Vision/eye Behavior/neurological Mortality/aging
15 No significant impact
2 Not tested
Data collections
Gene metrics:12Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| preweaning lethality, incomplete penetrance | 3 supporting datasets | Mapk6em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| no spontaneous movement | 1 supporting dataset | Mapk6em1(IMPC)Mbp | heterozygote | E18.5 | N/A * | ||
| abnormal eye morphology | 1 supporting dataset | Mapk6em1(IMPC)Mbp | heterozygote | Early adult | N/A * | ||
| abnormal placenta morphology | 1 supporting dataset | Mapk6em1(IMPC)Mbp | heterozygote | E18.5 | N/A * | ||
| abnormal brain morphology | 1 supporting dataset | Mapk6em1(IMPC)Mbp | heterozygote | Early adult | N/A * | ||
| edema | 1 supporting dataset | Mapk6em1(IMPC)Mbp | homozygote | E18.5 | N/A * | ||
| abnormal vitreous body morphology | 1 supporting dataset | Mapk6em1(IMPC)Mbp | heterozygote | Early adult | 5.99x10-5 | ||
| decreased brain size | 1 supporting dataset | Mapk6em1(IMPC)Mbp | heterozygote | Early adult | N/A * | ||
| increased startle reflex | 1 supporting dataset | Mapk6em1(IMPC)Mbp | heterozygote | Early adult | 2.75x10-5 | ||
| cataract | 1 supporting dataset | Mapk6em1(IMPC)Mbp | heterozygote | Early adult | 6.35x10-5 |
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External links
No external links available for Mapk6.
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| Mapk6em1(IMPC)Mbp | Exon Deletion | | mouse |
| Mapk6tm1(NCOM)Cmhd | Reporter-tagged deletion allele (with selection cassette) | | targeting vector ES Cell |