Crim1 | cysteine rich transmembrane BMP regulator 1

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Behavior/neurological Mortality/aging

16 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:2Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

preweaning lethality, complete penetrance1 supporting datasetCrim1em1(IMPC)WtsihomozygoteEarly adultN/A * 
trunk curl1 supporting datasetCrim1em1(IMPC)WtsiheterozygoteEarly adult2.06x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Crim1em1(IMPC)WtsiDeletionmouse
Crim1tm184348(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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