Sacs | sacsin
Physiological systems
21 / 24 physiological systems tested
8 Significantly impacted by the knock-out
Reproductive system Immune system Integument Hematopoietic system Behavior/neurological Skeleton Mortality/aging Renal/urinary system
13 No significant impact
3 Not tested
Data collections
Gene metrics:13Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| increased mean corpuscular volume | 1 supporting dataset | Sacsem1(IMPC)Tcp | heterozygote | Early adult | 4x10-8 | ||
| abnormal sternum morphology | 1 supporting dataset | Sacsem1(IMPC)Tcp | homozygote | Early adult | N/A * | ||
| increased startle reflex | 1 supporting dataset | Sacsem1(IMPC)Tcp | heterozygote | Early adult | 4.03x10-5 | ||
| abnormal kidney morphology | 1 supporting dataset | Sacsem1(IMPC)Tcp | heterozygote | Early adult | N/A * | ||
| increased mean corpuscular volume | 1 supporting dataset | Sacsem1(IMPC)Tcp | homozygote | Early adult | 2.58x10-6 | ||
| small uterus | 1 supporting dataset | Sacsem1(IMPC)Tcp | homozygote | Early adult | N/A * | ||
| abnormal skin morphology | 1 supporting dataset | Sacsem1(IMPC)Tcp | heterozygote | Early adult | N/A * | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Sacsem1(IMPC)Tcp | homozygote | Early adult | N/A * | ||
| abnormal spleen morphology | 1 supporting dataset | Sacsem1(IMPC)Tcp | homozygote | Early adult | N/A * |
| | | | | | | | | | |
External links
No external links available for Sacs.
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
| Sacsem1(IMPC)Tcp | Exon Deletion | | mouse |
| Sacstm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |