Nox4 | NADPH oxidase 4

GeneMGI:1354184

Physiological systems

21 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Growth/size/body region Hematopoietic system Cardiovascular system

16 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Allele:

Phy. System:



increased heart weight	1 supporting dataset	Nox4^tm1.1Hwsc	homozygote	Early adult	3.46x10^-5
enlarged lymph nodes	2 supporting datasets	Nox4^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal lymph node morphology	2 supporting datasets	Nox4^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
increased mean corpuscular volume	1 supporting dataset	Nox4^tm1.1Hwsc	homozygote	Early adult	7.25x10^-5
increased circulating creatinine level	1 supporting dataset	Nox4^em1(IMPC)Mbp	homozygote	Early adult	3.28x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Nox4.

Associated images

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Histopathology

There is no histopathology data found for Nox4.

IMPC related publications

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External links

No external links available for Nox4.

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*Nox4^em1(IMPC)Mbp*	Exon Deletion	‌	mouse

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