Cbarp | calcium channel, voltage-dependent, beta subunit associated regulatory protein

GeneMGI:1354170Synonyms: Dos, R29144/1

Physiological systems

17 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Growth/size/body region Vision/eye Behavior/neurological Skeleton

13 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:9Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal bone structure	1 supporting dataset	Cbarp^{tm2e.1(EUCOMM)Hmgu}	homozygote	Early adult	2.47x10^-5
abnormal eye anterior chamber depth	1 supporting dataset	Cbarp^{tm2e.1(EUCOMM)Hmgu}	homozygote	Early adult	9.2x10^-7
decreased body length	1 supporting dataset	Cbarp^{tm2e.1(EUCOMM)Hmgu}	homozygote	Early adult	7.94x10^-6
decreased locomotor activity	2 supporting datasets	Cbarp^{tm2e.1(EUCOMM)Hmgu}	homozygote	Early adult	2.89x10^-6
decreased exploration in new environment	1 supporting dataset	Cbarp^{tm2e.1(EUCOMM)Hmgu}	homozygote	Early adult	4.66x10^-7
hyperactivity	1 supporting dataset	Cbarp^{tm2e.1(EUCOMM)Hmgu}	homozygote	Early adult	7.12x10^-5
increased anxiety-related response	1 supporting dataset	Cbarp^{tm2e.1(EUCOMM)Hmgu}	homozygote	Early adult	9.31x10^-5
decreased vertical activity	1 supporting dataset	Cbarp^{tm2e.1(EUCOMM)Hmgu}	homozygote	Early adult	6.08x10^-7
decreased bone mineral content	1 supporting dataset	Cbarp^{tm2e.1(EUCOMM)Hmgu}	homozygote	Early adult	3.22x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Cbarp.

Associated images

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Histopathology

There is no histopathology data found for Cbarp.

IMPC related publications

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External links

No external links available for Cbarp.

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*Cbarp^{tm2a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Cbarp^{tm2e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	mouse
*Cbarp^{tm2e.1(EUCOMM)Hmgu}*	Promoter excision from Targeted, non-conditional allele	‌	mouse

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