Fgd3 | FYVE, RhoGEF and PH domain containing 3

GeneMGI:1353657Synonyms: ZFYVE5, 5830461L01Rik

Physiological systems

21 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Homeostasis/metabolism Reproductive system Immune system Endocrine/exocrine gland Hematopoietic system Behavior/neurological

15 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal seminal vesicle morphology1 supporting datasetFgd3em1(IMPC)CcpczhomozygoteEarly adultN/A * 
decreased leukocyte cell number1 supporting datasetFgd3em1(IMPC)CcpczhomozygoteEarly adult2.06x10-5 
decreased lymphocyte cell number1 supporting datasetFgd3em1(IMPC)CcpczhomozygoteEarly adult3x10-5 
decreased circulating creatinine level1 supporting datasetFgd3em1(IMPC)CcpczhomozygoteEarly adult1.59x10-5 
decreased exploration in new environment1 supporting datasetFgd3em1(IMPC)CcpczhomozygoteEarly adult4.11x10-6 
abnormal testis morphology1 supporting datasetFgd3em1(IMPC)CcpczhomozygoteEarly adultN/A * 
small testis1 supporting datasetFgd3em1(IMPC)CcpczhomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Fgd3em1(IMPC)CcpczExon Deletionmouse
Fgd3tm270455(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector
Fgd3tm40096(L1L2_gt2)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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