Glrx3 | glutaredoxin 3

GeneMGI:1353653Synonyms: PKC interacting cousin of thioredoxin, Txnl2, +1 more

Physiological systems

19 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Homeostasis/metabolism Mortality/aging

17 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

0Associated diseases

Expression examined in:48Adult tissues

25Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



increased circulating alkaline phosphatase level	1 supporting dataset	Glrx3^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	2.42x10^-5
embryonic lethality prior to tooth bud stage	1 supporting dataset	Glrx3^{tm1.1(KOMP)Vlcg}	homozygote	E12.5	N/A ^*
preweaning lethality, complete penetrance	1 supporting dataset	Glrx3^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
embryonic lethality prior to organogenesis	1 supporting dataset	Glrx3^{tm1.1(KOMP)Vlcg}	homozygote	E9.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Glrx3.

Associated images

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Histopathology

There is no histopathology data found for Glrx3.

IMPC related publications

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External links

No external links available for Glrx3.

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*Glrx3^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Glrx3^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Glrx3^{tm383784(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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