Fus | fused in sarcoma

GeneMGI:1353633Synonyms: pigpen, hnRNP P2, +4 more

Physiological systems

19 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Homeostasis/metabolism Embryo Growth/size/body region Nervous system Mortality/aging

14 No significant impact

5 Not tested

Gene metrics:5Significant phenotypes
7Associated diseases
Expression examined in:41Adult tissues
50Embryo tissues

Phenotypes

increased prepulse inhibition3 supporting datasetsFustm1.1(KOMP)VlcgheterozygoteEarly adult1.74x10-6 
increased respiratory quotient1 supporting datasetFustm1.1(KOMP)VlcgheterozygoteEarly adult2.39x10-5 
preweaning lethality, complete penetrance3 supporting datasetsFustm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
abnormal embryo size1 supporting datasetFustm1.1(KOMP)VlcghomozygoteE15.5N/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Fustm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Fustm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse
Fustm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Fustm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell
Fustm236153(L1L2_gt1)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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