Siva1 | SIVA1, apoptosis-inducing factor

GeneMGI:1353606Synonyms: CD27bp

Physiological systems

19 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Homeostasis/metabolism Vision/eye

17 No significant impact

5 Not tested

Gene metrics:2Significant phenotypes
0Associated diseases
Expression examined in:70Adult tissues
0Embryo tissues

Phenotypes

abnormal lens morphology2 supporting datasetsSiva1tm1b(EUCOMM)HmguhomozygoteEarly adult1.66x10-6 
increased fasting circulating glucose level1 supporting datasetSiva1tm1b(EUCOMM)HmguhomozygoteEarly adult2.04x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Siva1tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Siva1tm1b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse

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