Siva1 | SIVA1, apoptosis-inducing factor

GeneMGI:1353606Synonyms: CD27bp

Physiological systems

19 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Homeostasis/metabolism Vision/eye

17 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

0Associated diseases

Expression examined in:70Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal lens morphology	2 supporting datasets	Siva1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	1.66x10^-6
increased fasting circulating glucose level	1 supporting dataset	Siva1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	2.04x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Siva1.

Associated images

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Histopathology

There is no histopathology data found for Siva1.

IMPC related publications

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External links

No external links available for Siva1.

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*Siva1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Siva1^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse

My Genes