Pdlim4 | PDZ and LIM domain 4

GeneMGI:1353470Synonyms: Ril

Physiological systems

18 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Homeostasis/metabolism Endocrine/exocrine gland Limbs/digits/tail Behavior/neurological Skeleton

13 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:8Significant phenotypes

1Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased locomotor activity	1 supporting dataset	Pdlim4^em1(IMPC)Ics	homozygote	Early adult	7.44x10^-6
short tibia	2 supporting datasets	Pdlim4^em1(IMPC)Ics	homozygote	Early adult	3.34x10^-5
increased anxiety-related response	1 supporting dataset	Pdlim4^em1(IMPC)Ics	homozygote	Early adult	2.9x10^-5
abnormal pancreas morphology	1 supporting dataset	Pdlim4^em1(IMPC)Ics	homozygote	Early adult	N/A ^*
abnormal behavior	1 supporting dataset	Pdlim4^em1(IMPC)Ics	homozygote	Early adult	4.47x10^-5
increased thigmotaxis	2 supporting datasets	Pdlim4^em1(IMPC)Ics	homozygote	Early adult	4.47x10^-5
improved glucose tolerance	1 supporting dataset	Pdlim4^em1(IMPC)Ics	homozygote	Early adult	5.69x10^-6
decreased circulating glucose level	1 supporting dataset	Pdlim4^em1(IMPC)Ics	homozygote	Early adult	9x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Pdlim4.

Associated images

Loading...

Histopathology

There is no histopathology data found for Pdlim4.

IMPC related publications

Loading...

External links

No external links available for Pdlim4.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Pdlim4^em1(IMPC)Ics*	Exon Deletion	‌	mouse
*Pdlim4^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Pdlim4^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	es cell
*Pdlim4^{tm2a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Pdlim4^{tm301216(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*Pdlim4^{tm37806(pL1L2_GT2_DelLacZ_bsd)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

My Genes