Pdlim4 | PDZ and LIM domain 4

GeneMGI:1353470Synonyms: Ril

Physiological systems

18 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Homeostasis/metabolism Endocrine/exocrine gland Limbs/digits/tail Behavior/neurological Skeleton

13 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:8Significant phenotypes

1Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased locomotor activity	1 supporting dataset	Pdlim4^em1(IMPC)Ics	homozygote	Early adult	7.44x10^-6
short tibia	2 supporting datasets	Pdlim4^em1(IMPC)Ics	homozygote	Early adult	3.34x10^-5
increased anxiety-related response	1 supporting dataset	Pdlim4^em1(IMPC)Ics	homozygote	Early adult	2.9x10^-5
abnormal pancreas morphology	1 supporting dataset	Pdlim4^em1(IMPC)Ics	homozygote	Early adult	N/A ^*
abnormal behavior	1 supporting dataset	Pdlim4^em1(IMPC)Ics	homozygote	Early adult	4.47x10^-5
increased thigmotaxis	2 supporting datasets	Pdlim4^em1(IMPC)Ics	homozygote	Early adult	4.47x10^-5
improved glucose tolerance	1 supporting dataset	Pdlim4^em1(IMPC)Ics	homozygote	Early adult	5.69x10^-6
decreased circulating glucose level	1 supporting dataset	Pdlim4^em1(IMPC)Ics	homozygote	Early adult	9x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Pdlim4.

Associated images

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Histopathology

There is no histopathology data found for Pdlim4.

IMPC related publications

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External links

No external links available for Pdlim4.

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*Pdlim4^em1(IMPC)Ics*	Exon Deletion	‌	mouse
*Pdlim4^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Pdlim4^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Pdlim4^{tm2a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Pdlim4^{tm301216(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*Pdlim4^{tm37806(pL1L2_GT2_DelLacZ_bsd)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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