Cttnbp2 | cortactin binding protein 2

GeneMGI:1353467Synonyms: 9130022E09Rik, Cortbp2, +3 more

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Immune system Hematopoietic system Behavior/neurological

15 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

0Associated diseases

Expression examined in:45Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased memory CD4-positive, CD25-positive, alpha-beta regulatory T cell number	1 supporting dataset	Cttnbp2^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
increased plasma cell number	1 supporting dataset	Cttnbp2^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
increased grip strength	2 supporting datasets	Cttnbp2^{tm1b(KOMP)Wtsi}	homozygote	Early adult	5.7x10^-5
decreased transitional stage T1 B cell number	2 supporting datasets	Cttnbp2^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Cttnbp2.

Associated images

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Histopathology

There is no histopathology data found for Cttnbp2.

IMPC related publications

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External links

No external links available for Cttnbp2.

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*Cttnbp2^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Cttnbp2^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Cttnbp2^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	es cell

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